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They're upright because they're trying to mimic the letter "i" which also stands upright and also happens to be the way you spell out this character in romaji 1

According to NICE guidance, referral to a hepatologist should be considered for patients with advanced fibrosis (indicated by non-invasive tests), persistently abnormal liver function tests despite lifestyle modification, or diagnostic uncertainty

But try the original German ones, and everything will start to make sense

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Dimensions: 4614 x 3503 px | 39.1 x 29.7 cm | 15.4 x 11.7 inches | 300dpi Date taken: 27 October 2016 Photographer: Karl F

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