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The University of North Carolina Press

55 Further, NRT-assisted smoking reduction is associated with increased cessation rates among smokers unmotivated to quit

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[30] Popularization [edit source] In 1612, six years after the settlement of Jamestown, Virginia, John Rolfe was credited as the first settler to successfully raise tobacco as a cash crop

Compared with those who sustained their cigarette consumption, quitting was associated with a reduced risk of both stroke (aHR 0.77, 95% CI 0.740.81) and heart attack (aHR 0.74, 95% CI 0.700.78)