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Higher relative abundance of proinflammatory bacteria like Eggerthella, Atopobium was found to be increased, and decreased relative abundance of Faecalibacterium in the subjects with MDD (Knudsen et al., 2021)

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This blockade leads to rapid accumulation of norepinephrine within the synaptic cleft and prolonged activation of postsynaptic adrenergic receptors, producing enhanced sympathomimetic activity

For example, Lactobacillus rhamnosus probiotic can reduce cocaine-induced behavioral responses (220)

[DOI] [PubMed] [Google Scholar] 47.Ottestad I, Vogt G, Retterstol K, Myhrstad MC, Haugen JE, Nilsson A et al