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However, a dysregulated increase in the level of these free radicals, as seen in mitochondrial diseases, can result in oxidative damage by overwhelming the cellular antioxidant defence mechanism, of which glutathione is the principal component [4]

The Role of Supplements in Restoring Glutathione: Supplements, particularly NAC, are known to effectively replenish glutathione levels in the body

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Reactions of nitrogen-dioxide in aqueous model systemsOxidation of tyrosine units in peptides and proteins

Valko MM, Morris H (2005) Cronin MT (2005) Metals, toxicity and oxidative stress

Lei G, Zhang Y, Koppula P et al (2020) The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression