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Tamura, et al
This gives a concentration of 50 mg per ml , which works out to 0.5 mg per unit on a 1 ml insulin syringe
Studies of this kind must be regarded as tentative, however, as there were not adequate controls in the study including a lack of randomization, double-blinding, or placebo
They further noted that oral pills do not require refrigeration, a factor that could widen the reach of obesity care in many regions of the world where lack of refrigeration is a barrier to access. The 71-week, double-blind, randomized trial enrolled 307 participants without diabetes across four countries
the CagriSema combination NDA is under review and retatrutide is at the Phase 3 stage
GLP-1 has been proposed to have a role in lung protection (105), although this has primarily been described in rodents, where the GLP-1R is expressed at higher levels (87) and also in more diverse cell types (e.g., type 2 pneumocytes) than in humans (106)
