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Health was always a concern, like causing throat dryness which the cigarette companies combatted by promoting brands marketed as less irritating

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It also flushes or removes any food particles stuck on the surface of the teeth or in-between two teeth

They increase epithelial permeability caused by tight junction damage, stripping the mucociliary epithelial barrier and leading to a compromised defense mechanism against pathogens, peribronchial inflammation, oxidative stress, and ultimately, a more detrimental immune response (Figure 1)