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Historically, best practice for patients with active substance use disorder required caution about assigning mental illness diagnoses such as anxiety or depression as most symptoms would remit with abstinence alone

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Sometimes the question, and the frustration, is digital, not practical or prosthetic, as in the case of The Irishman. I like that film enormously, but even with all the millions Martin Scorsese spent on de-aging his stars in some scenes, I came away thinking: How hard would it have been to find the right unknowns to play younger versions of De Niro, Pacino and Pesci

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