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Patients with Hepatic impairment - Hepatic impairment does not have any impact on the exposure of semaglutide

Maintenance dosing with 60 mg vials Once you have titrated to your target dose, the 60 mg vial becomes straightforward: At a 10 mg maintenance dose, you need roughly 9 vials per year

Another good option is the thigh , the outer part halfway between your hip and knee

When combining these agents, patients may experience additive gastrointestinal effects, though clinical trial data suggest the combination is generally well-tolerated when appropriate dose titration strategies are employed

The side effects at higher doses are not necessarily worse than at lower doses, just recurring

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