Shi R, Hamzaoui O, De Vita N, Monnet X, Teboul JL
S., Anic, T., Seiwerth, S., & Sikiric, P
Answer: The most common side effects of amylin analogs are gastrointestinal, including nausea, reduced appetite, and occasional vomiting or constipation, and they are usually mild, dose-related, and managed by slow titration
Imaging studies have shown, for example, that a potentiated synapse can exhibit spine growth, whereas non-stimulated neighboring synapses might shrink [11] These structural modifications help lock in the functional changes, making the potentiation more durable
We discuss the multi-agonists currently in clinical trials and how each new generation of these drugs improves their effectiveness
J Pharmacol Exp Ther 311:99108 Clancy RM, Levartovsky D, Leszczynska-Piziak J, Yegudin J, Abramson SB (1994) Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary