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A particularly fascinating aspect of reactive microglia in neurodegeneration is their dynamic receptor expression profilewhile these receptors are nearly undetectable in resting microglia, they become markedly upregulated upon activation

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The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity

Bell FP, Vidmar TJ, Raymond TL

56 (2 of 2): 14058 Kelly GS

Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen