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When THC enters the body, it can bind to CB1 receptors, leading to the activation of inflammatory pathways

A recent paper attempted to triangulate individual- and population-level data and concluded that the 'causal claims about a strong gateway effect from e-cigarettes to smoking are unlikely to hold, while it remains too early to preclude other smaller or opposing effects'

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10.1002/hep.510290351 57

In the meantime during the pursuit, Id take some time out of every week to becomfortable

You get almost all the nicotine and flavor it can provide in that timeframe