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What makes retatrutide different from other GLP-1s is that its a triple agonist, sometimes nicknamed triple G, because it targets three hormone pathways at the same time: GLP-1 (glucagon-like peptide-1): Found naturally in your gut, this hormone helps lower blood sugar by triggering insulin release and slowing down how fast food moves through the stomach, so you feel fuller for longer

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A reappraisal