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In the first phase (acute), CN was metabolized fast into SCN

Would patients, already pushed to capacity, get violent, or worse

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I am simply suggesting that you've been living in here, Rumpole, sleeping rough

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Also, due to the generation of ROS by hampered neurons, such as dysfunction of mitochondria, perodixation of lipids, and DNA damage, leading to apoptosis of neurons [60,61,62,63]