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The activation of SREBP by mTORC1 also increases flux through the pentose phosphate pathway, leading to the production of NADPH and other intermediate metabolites necessary for cellular proliferation and growth

After it wears off, the brain is depleted of its dopamine, and depression is a common result

It is estimated that about one billion adults, the world over, had hypertension in the year 2010 and the number is expected to rise to 1.56 billion in the year 2025 if positive intervention programme is not made (1)

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