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Lerman C, Schnoll RA, Hawk LW Jr., Cinciripini P, George TP, Wileyto EP, et al

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Simply, mononuclear cells were isolated from bone marrow, inoculated in a culture bottle, incubated with EGM-2 (Lonza, Switzerland), and placed in an atmosphere at 37C, 95% humidity and 5% CO 2

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These data suggest that the inhibitory effect of IL-13/IL-13R1 on the activation of HCN channels is mediated by enhancing the PI3K/AKT signaling, rather than by changes in HCN protein expression