The TSCE model incorporates the impact of age-dependent carcinogen exposures, such as smoking, on the dynamics of lung cancer initiation, promotion, and malignant conversion, which allows for explicit examination and group comparisons of smoking-related and non-smoking-related (background) lung cancer risk
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However, since some of the e-cigs are modifiable by the user, smokers can alter the amount of nicotine inhaled by increasing the puff duration or the smoking interval
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Refraining from tobacco intake causes physical and psychological symptoms such as irritability, anxiety, difficulty concentrating, restlessness, frustration, depressive mood, increased hunger, anger, constipation, insomnia or diarrhoea
