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Moreover, miRNA-486-5p upregulation in exosomes can repress FLS proliferation and migration, which proves exosomes to be a suitable vector for the delivery of therapeutic miRNA-486-5p (283)

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There were no significant differences in respiratory rate between the groups at any time point, except for measurements at 50 min ( p = 0.025) and 120 min ( p = 0.012) after administration, where patients receiving Dex by any route had lower respiratory rates (Figure 3B)

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Bioavailability refers to the amount of a nutrient that actually reaches the systemic circulation and is available for the body to use