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This trend may partially reflect the fact that the implementation of anti-smoking laws, smoking bans in public outdoor spaces, and improvements in waste management infrastructure in many countries have not been fully effective in reducing cigarette butt contamination over the past decade

Acknowledgements This project was supported by National Institutes of Health/National Institute of General Medical Sciences Centers of Biomedical Research Excellence (NIH/NIGMS COBRE): South Carolina Translational Research Improving Musculoskeletal Health (SCTRIMH

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