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many patients continue treatment with monitoring Single episode of biliary colic: usually an indication for cholecystectomy, after which GLP-1 therapy can typically continue uninterrupted Acute cholecystitis or other complication: urgent surgical management, with GLP-1 therapy paused and reintroduced after recovery The decision is individualised and made jointly with your prescribing clinician

IL1 stimulation markedly increased IL6, TNF, COX2, and MMP13 expression in chondrocytes, whereas OSR treatment suppressed these markers in a dosedependent manner (Fig

Double-immunofluorescence staining of GLP-1R and -smooth muscle actin (-SMA) in kidney sections confirmed the absence of GLP-1R expression in VSMCs of Glp1r VSM/ mice (Figure 1M)

Free Radical Biol Med 37:19211942

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