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The authors of the 2025 study from the University of Turin suggest that the combination of L-carnitine and selenium may have a synergistic effect, and that L-carnitine may also have an immunomodulatory role, and its actions are not limited to peripheral thyroid hormone antagonism

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In contrast, LCACs are thought to have the potential to activate inflammation, activating the NF-B luciferase reporter gene in RAW 264.7 cells in an acyl chain length- and concentration-dependent manner, as well as the phosphorylation of JNK and ERK [54, 55]

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