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Enhanced membrane translocation of protein kinase C (i.e., activation) provides a potential mechanism for diacylglyceride-induced insulin resistance, suggesting hepatic diacylglyceride to be a relevant predictor of insulin resistance in NAFLD [72, 73]

Munich Re has previously published on the topic, including in our most recent Life Sciences Report, where we examined how these drugs may positively impact numerous drivers of obesity-related mortality, with an added scenario predicting a positive mortality effect in those with both moderate and severe obesity within insured populations

doi:10.1155/2015/545467

So, it's possible the effects aren't identical to those of traditional weight loss

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