Calcium and vitamin D intake, along with regular exercise, can help mitigate this risk
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Individuals with moderate glutathione synthetase deficiency may experience symptoms beginning shortly after birth including hemolytic anemia, 5-oxoprolinuria, and elevated acidity in the blood and tissues (metabolic acidosis)
Individuals with autoimmune conditions, active malignancy, or severe organ dysfunction should obtain explicit clearance
A few animal studies [73,74] would suggest that serine, a nonessential amino acid, may be helpful in positively influencing glutathione production, potentially through increased cysteine availability and a decrease of hypermethylation