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The orexigenic effect is mediated through GHSR-1a activation of NPY/AgRP neurons in the hypothalamus, with downstream engagement of reward circuits in the ventral tegmental area (Ghrelin signaling in VTA, 2015)

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Targeting ferroptosis against ischemia/reperfusion cardiac injury

(2020) found BPC-157 to be well tolerated at high doses in animal models

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