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Drinking lots of water is also beneficial when it comes to getting nicotine out of your body - both nicotine and its metabolite, cotinine, are water soluble, and so drinking lots of water not only helps get them out of your system, but the increased frequency of urination will encourage more nicotine and its metabolites to be excreted (3)
[86] The deleterious effects of CO are more profound in the myocardium than in peripheral tissues, because of the very high oxygen extraction by the myocardium at rest
Cochrane Database of Systematic Reviews, 11:CD004150
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Consider the texture and feel of the product: Pouches or Loose: Some alternatives come in the form of pouches, similar to traditional dip, while others are loose
