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The study showed no significant difference in stroke risk between past smokers and those who had never smoked

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Notably, CSE exposure during iTreg differentiation induced a time-dependent increase in SMAD3 and STAT5 phosphorylation in nave CD4 T cells isolated from Gpr15 +/+ mice (Supplementary Fig

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6.3 Mitochondria-targeted antioxidants and redox modulation Since mitochondrial reactive oxygen species (mtROS) are a key upstream trigger for mitophagy, targeting mitochondrial antioxidants has been explored as an indirect regulator of mitochondrial quality control (Zinovkin et al., 2023)