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This is exemplified by the association of EGR1 and MAP3K8 with lipid metabolism pathways in our analysis, suggesting that palmatine s multi-target intervention simultaneously addresses metabolic dysregulation and its consequential cell death, thereby offering a cohesive mechanism for its therapeutic efficacy in MASLD

Yano JM, Yu K, Donaldson GP, Shastri GG, Ann P, Ma L, Nagler CR, Ismagilov RF, Mazmanian SK, Hsiao EY

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