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The liver can use this mechanism to convert fatty acids into ketone bodies via acetyl-CoA and acetoacetyl-CoA as an additional source of energy for all tissues, but especially for the brain

Anderson HL, Brodsky IE, Mangalmurti NS

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Dose Titration We start patients at a conservative dose and titrate upward over the first 8 to 12 weeks based on response and tolerance

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Decreased expression of GST pi is correlated with a poor prognosis in human esophageal squamous carcinoma