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Semaglutide is considered to control energy intake and reduce body weight probably by activating at discrete sites in the hypothalamus to reduce food craving, or by delaying the gastric emptying to affect appetite (119, 177, 178)

doi: 10.3389/fimmu.2026.1744308 Received 11 November 2025 Revised 04 April 2026 Accepted 13 April 2026 Published 28 April 2026 Volume 17 - 2026 Edited by Francesco Caso, University of Naples Federico II, Italy Reviewed by Piero Ruscitti, University of LAquila, Italy Silvia Scriffignano, Fondazione Istituto G.Giglio, Italy Updates Copyright 2026 Ciancio, Maranini, Sandri, Amati, Bortoluzzi, Silvagni, Govoni and Giuggioli

Br J Dermatol (2020) 182(4):8408

Test the broader biochemical pattern When mood, OCD traits, sleep, allergies or treatment response remain unexplained, consider whole-blood histamine, biotype labs and direct methylation testing

Digestive Diseases and Sciences, 49 , 65-72

Yarizadh, S