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Their relative incidence is completely different in adults and in children: 73% of single-digit lesions in adults are due to melanocytic activation, while 75% of single-digit lesions in children are due to benign melanocytic hyperplasia, mainly nevi

Aside from increasing appetite, cortisol also activates glucocorticoid receptors, which are densely concentrated in visceral fat depots

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While these symptoms have many potential causes, they require evaluation to rule out thyroid pathology, given the FDA's boxed warning regarding thyroid C-cell tumors

Importantly, a growing trend of obesity and diabetes was observed in nearly all countries due to global urbanization, unhealthy diets, high body mass index, and increasing income