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Tirzepatide is administered once weekly on the same day each week and can be taken any time of day, with or without food

(See our guides on foods to avoid and supplements to consider ) What happens if I need to switch between medications

Zepbound changes how your body handles food by slowing down how fast your stomach empties

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The weight loss timeline typically shows more significant results during this period

Tirzepatide works by activating GLP-1 and GIP receptors in your brain and gut, creating sustained appetite suppression that typically peaks 24 to 48 hours after injection