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4.1 Natural products remodel tumor microenvironment through immune cell metabolic reprogramming With increasing insights into the mechanisms by which natural products modulate metabolism in cancer, studies have found that these natural products have the potential to reshape the TME by reprogramming immune cell metabolism and restoring antitumor immunity

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PRMT6 epigenetically drives metabolic switch from fatty acid oxidation toward glycolysis and promotes osteoclast differentiation during osteoporosis