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doi: 10.4077/CJP.2018.BAG521

Genetic susceptibility, DNA methylation changes, local chronic lung inflammation, and abnormal repair mechanisms in COPD patients are important potential factors for lung cancer development [58,59,60]

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FEATURED IMAGE BY NICOLASMCCOMBER/E+/GETTY IMAGES PLUS From Decisions in Dentistry

Robert West, director of tobacco studies at the Health Behaviour Research Unit, University College London, who carried out the study, said: "These figures show the largest fall in the number of smokers on record