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6 Adjusting the doses of medicines Smoking tobacco causes exposure to particulates that induce enzymes involved in the metabolism of certain medicines, such as clozapine, selective serotonin reuptake inhibitors (SSRIs) and warfarin

Shellac-based and oil-based primers are the strongest options because they: Seal smoke residue so it cant escape Prevent brown or yellow nicotine stains from bleeding through Create a stable base for the topcoat A widely used example is Zinsser B-I-N, which is known for its strong odour-sealing performance