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Future studies will be of interest to assess whether the airway epithelial structure and function of mitochondria differs between in young non-smoking individuals who are non-susceptible and susceptible to develop COPD

Likewise, heavier smokers should aim for a higher strength to ensure their nicotine needs are being met without having to use the product more than necessary

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New Scientist

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Another study showed that compared to air-exposed controls, IQOS-exposed mice (14 days) had significantly decreased concentrations of reduced glutathione and increased percentage of oxidized glutathione in lung tissues, both markers of oxidative stress 44