3rd generation glp 1 There's a new name in the conversation — and it's worth paying attention to. Retatrutide is a triple-agonist therapy that targets GLP-1, GIP, and glucagon receptors simultaneously. In clinical trials, it GLP-1 receptor agonists and next-generation

Tirzepatide and retatrutide (single molecule): A single engineered molecule that hits multiple receptors simplifies the formulation to one compound with one pharmacokinetic profile, and allows the balance of receptor activation to be tuned at the molecular-design level

Intramuscular (IM) Injection Near the Tendon: This involves injecting into the muscle tissue adjacent to the tendon

10.1210/en.2017-00872 468 VashiR.PatelB

In muscle tissue of aged mice, lowered level of pro-inflammatory markers IL-1, TNF-, and IL-6 was observed after GLP-1RA dulaglutide treatment (Khin et al., 2021

This is one reason the researchers tested whether treating inflammation and weight at the same time could help

Current Opinion in Anaesthesiology