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When miR-146a levels rise, two key TLR signaling proteins, IRAK1 and TRAF6, may decrease, and thus they may not transmit inflammatory signals inside the cell, including pathways linked to NF-B activation, which would otherwise play a major role in inflammatory signaling

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Cell Mol Life Sci 2013;70:63159

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6,149 At the apical membrane, PTEN catalyzes the formation of PIP2 and the removal of PIP3