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Tomida I, Azuara-Blanco A, House H, Flint M, Pertwee RG, Robson PJ

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95% CI, 13 to 17).1 (Strength of Recommendation: A, consistent, good-quality patient-oriented evidence.) More people discontinue using bupropion due to adverse effects than those using placebo or no pharmacological treatment (number needed to harm [NNH] with 150 to 300 mg of bupropion daily to result in one patient quitting = 33