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Extended continuous daily administration risks progressive receptor desensitization that would diminish the compound's effectiveness over time

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Once infected, either by exogenously supplied transmissible seed (e.g., scrapie inoculation by oral or intraperitoneal administration

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The brain also signals the adrenal glands to release adrenaline (epinephrine), a hormone that causes the breakdown of glycogen into glucose, which can then be used as an energy source

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