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Yes, you will need to stop taking any psychoactive medications, smokeless tobacco, smoking cessation medications, nicotine products, beta-adrenergic medications, or other blood pressure medications to participate in this trial

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Its signature profile is achieved through an aging process involving herbal extracts, resulting in a unique plum-like fragrance

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Guthrie, Arlo (1967)

As a result, little is known about how smokers experience reduced-nicotine cigarettes when they are actually aware of the reduced content and how this knowledge may impact their use of these cigarettes