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Other constituents, such as vinyl chloride, have a well-established association with hepatic angiosarcoma [28], whereas cadmium enhances liver cancer risk through proto-oncogene activation, oxidative stress induction, and stimulation of pro-inflammatory cytokines [2931]

Table 2 reports the regression of the log of per capita tobacco expenditure on log of cigarette prices

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Nicotine and cotinine stimulate secretion of basic fibroblast growth factor and affect expression of matrix metalloproteinases in cultured human smooth muscle cells