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A missense variant in AIFM1 caused mitochondrial dysfunction and intolerance to riboflavin deficiency

Dose from 1 mg to 20 mg is found suitable if sufficient sustained action and sufficient amount of penetration enhancers are employed

Dual-energy X-ray absorptiometry (DEXA) and computed tomography observations have been used in research to evaluate these outcomes, which appeared to suggest measurable changes in bone mineral content

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