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10.1074/jbc.M109.060178 52

What the MTHFR Gene Affects Many people dont know they have an MTHFR mutation because testing is not routinely performed

Side Effects and Safety Profile Common side effects are mostly gastrointestinal and dose-dependent, including nausea, vomiting, diarrhea, constipation, and decreased appetite

Comment As in the case of hemangiomas, the occurrence of hemangiosarcomas in rodents has been well described in the published literature (Binhazim, Coghlan, and Walker 1994;Booth and Sundberg 1996

Athletes and active individuals who supplement with L-Carnitine often report reduced lactic acid buildup in muscle tissue, which may help delay fatigue and extend workout capacity

So it's really interesting