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Meanwhile, mitochondrial damage mediated by PCD protein 2 can increase the generation of mitochondrial reactive oxygen species, synergistically inducing autophagy and ferroptosis [113]

Bortezomib-induced peripheral neurotoxicity: a neurophysiological and pathological study in the rat

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However, investigation of the effect of UA on such models is limited by the profound differences between humans and e.g., rodents in UA metabolism, primarily due to the loss in humans of a functional uricase

N., & Radi, R

The test lasts about 12 minutes, starting easy and increasing in difficulty by increments until you tap out from exhaustion