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In 2009, Health Canada issued an advisory against the nicotine-containing product, as insufficient evidence was available to support its sale

By type, sales of traditional cigarettes fell 2.8 percent on-year to 3 billion packs last year, while those of heat-not-burn electronic cigarettes advanced 12.6 percent to 610 million packs

Our new study adds an important piece to that puzzle by demonstrating that epigenetic mechanisms, specifically changes in chemical tags attached to the DNA, may contribute to the abnormal expression of genes in vapers and smokers alike, Besaratinia said

The regulatory compliance burden in the US, especially under the FDAs premarket tobacco application (PMTA) framework, adds another layer of complexity

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