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This hypothesis was supported by results that also OPC differentiation was significantly induced, axons were re-wrapped, and axonal damage was reduced after T4 treatment at the late stage of EAE (day 30 after onset), and that OPC differentiation significantly correlates with the neurological functional score (Zhang et al., 2016a)

Anyone dismissing it as pure placebo is ignoring the mechanistic foundation and the accumulating clinical signals

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M., Seliger, S., Lakshminarayan, K., Herzog, C

Cerebral blood flow measured by arterial spin labeling MRI at resting state in normal aging and Alzheimers disease