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[1] [2] Increasing levels of CD38, a membrane-bound NADase that destroys both NAD+ and its precursor nicotinamide mononucleotide, are thought to be the cause of the age-related decline in NAD+ levels, according to a 2016 study in mice, which exhibit age-related declines in NAD+ levels similar to those seen in humans

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These effects were dose-dependent, with the 54 mg dose (substantially higher than standard protocols) showing increased GI-related events

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Glycine propionyl-L-carnitine produces enhanced anaerobic work capacity with reduced lactate accumulation in resistance-trained males

If you drink excessively, then it may rather increase the risk of hypoglycemia