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Vaccines 12(11):1260 AL-Bashaireh AM, Haddad LG, Weaver M, Kelly DL, Chengguo X, Yoon S (2018) The effect of tobacco smoking on musculoskeletal health: A systematic review

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Tobacco smoke contains irritating substances (a mixture of more than 7,000 chemicals) and when inhaled, it irritates the linings of the lungs

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"There's a growing public perception that marijuana is harmless or even beneficial," Wu said, comparing the legalization of marijuana use to vaping, which was first marketed as a safe way to stop smoking but has since been shown to cause lung damage and lead to increased tobacco use