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If you experience troublesome symptoms whilst taking self-initiated B12 supplements, temporarily discontinuing them whilst awaiting GP review is reasonable

For instance, trigeminal neuralgia is more prevalent in individuals over 50, with a higher incidence among women

Dietary intake: Vegetarians, vegans, and those who limit their daily consumption of animal products may have to consume more vitamin B12, as it is mainly present in foods of animal origin

Always factor this into your experimental design

Some studies suggest that people with obesity may be more likely to have a vitamin B12 deficiency

its unique cationic properties bind tightly to negatively charged drug molecules, forming stable complexes, and interact electrostatically with the negative charges on the mucosal surface (Sinha et al., 2004