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Compared to non-smoking-related lung cancer, rare sensitizing and non-sensitizing EGFR mutations are more likely to occur in smoking-related lung cancer cases

While this can support weight loss, it also increases the risk of lean muscle loss if protein intake is too low

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The MRP2 expression vector pcDNA5/FRT-MRP2 was constructed by cloning the ABCC2 gene into the eukaryotic expression vector pcDNA5/FRT (Life Technologies) as described previously 59 with an additional Kozak sequence added at the beginning of the gene