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Patients should be advised that tirzepatide is not a controlled substance and does not carry abuse potential like stimulant medications

Through such synergistic cooperation, the two jointly enhance the autophagic activity of the cells [49]

The strongest body-weight meta-analysis found a modest average reduction of about 1.21 kg, with the best dose-response signal near 2,000 mg/day, mostly in adults with overweight or obesity

It is not known whether this occurs in humans

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It blocks fat absorption in the gut rather than acting on appetite hormones